ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

Blog Article

ETNK1 mutations are recurrent in leukemia but how they contribute to oncogenesis is still unclear.Here, the authors sophie allport zebra show that ETNK1 mutations increase mitochondrial activity, ROS and H2AX levels and that read more these effects can be rescued upon phosphoethanolamine supplementation.